The Left and Top properties of the components on the datamodule as well as its Width and Height are stored in the DFM. When you design a datamodule on a system with 200% scaling and open that later on a system with 100% scaling the datamodule would be shown twice as large. The other way round, when you design a datamodule with 100% (like all datamodules created in previous Delphi versions) and open that on a 200% system, most of the components and their names would probably overlap, because the icons and fonts are scaled in the designer (otherwise they were way too small). When Delphi 11 opens one of those old datmodule it correctly assumes that it was designed with 100% and scales it to 200%. When saving would omit to store the used PixelsPerInch value in the DFM the (already scaled) datamodule would be treated as designed in 100% according to the scheme described and scaled again.
Don't get me wrong: I think this is the wrong approach. Scaling for designing is good, but when saving it should be forced to downscale to 96 PPI again. That way the additional PixelsPerInch property in the DFM can be removed. I also suggest to adopt this behavior for forms and frames accordingly.